Retinal self-organization: a model of retinal ganglion cells and starburst amacrine cells mosaic formation

 Researchers from the University of Newcastle upon Tyne and the University of Surrey have just published a new article where they presented realistic simulations of retinal cell self-organization built using BioDynaMo and biological data from in vitro experiments and from the literature.

You can check the paper online here


Comments

Post a Comment

Popular posts from this blog

PhD Studentship: AI-assisted design of cryoprotective agents

 Interested in AI and biology? Then this PhD studentship could be for you! Thousands of donated organs are discarded each year because current preservation methods allow storage for only a few hours. Cryopreservation at ultra-low temperatures offers the prospect of long-term organ banking, but its application to large tissues and organs is limited by ice crystal formation and the toxicity of existing cryoprotective agents (CPAs). Overcoming these challenges is a major unmet need in biomedicine. This interdisciplinary PhD project aims to develop AI-driven approaches to discover safer and more effective CPAs by integrating machine learning, computational modelling, and experimental validation. The successful candidate will receive training in both computational and experimental biology within a highly collaborative research environment. The project will begin with the construction of a curated database from the literature, capturing known CPAs, their properties, concentrations, and ...
Read more

Modelling lung cells to personalize radiotherapy (with BioDynaMo) among the Top 10 Breakthroughs of the Year in physics for 2024!

Image
 Last December the 12th Physics World has delighted announced its Top 10 Breakthroughs of the Year for 2024, which includes research in nuclear and medical physics, quantum computing, lasers, antimatter and (of course ^_^) BioDynaMo . The Top Ten is the shortlist for the Physics World Breakthrough of the Year, which will be revealed on Thursday 19 December. PhysicsWorld editorial team has looked back at all the scientific discoveries reported on since 1 January and has picked 10 they judge are the most important. In addition to being reported in Physics World in 2024, the breakthroughs must meet the following criteria:  Significant advance in knowledge or understanding Importance of work for scientific progress and/or development of real-world applications Of general interest to Physics World readers  You can listen to the editors making their case for the research in the Top10 in this podcast What do they say about the BioDynaMo research they selected: <<Modelling...
Read more

New vacancy with BioDynaMo: Research Assistant at the Univ. of Cyprus

Image
Would you like to conduct fundamental and/or applied research on “Brain Neuronal Networks Development via Multiscale Agent-based Modelling"? Don't miss this "Special Scientist - Post-Graduate Researcher (Research Assistant)" vacancy at the University of Cyprus, funded by the Foresight Institute   A great opportunity to join the # BioDynaMo team and work with Roman Bauer and Vasileios Vavourakis Project description : In this project, REASON, we will demonstrate an innovative computational approach to model and emulate biological NNs: rather than directly modelling a brain with all its complexity, we will model NN development from a single precursor cell. In other words, by leveraging the same approach that nature uses to build brains, we aim to reproduce challenging neural complexities. Inspired by the biological brain, we will make use of developmental rules that are encoded in a gene-type manner. For instance, a rule could be that a given neural stem cell should ...
Read more